| Item Type | Name |
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Concept
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Cognitive Dysfunction
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Academic Article
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Obesity in Aging Exacerbates Neuroinflammation, Dysregulating Synaptic Function-Related Genes and Altering Eicosanoid Synthesis in the Mouse Hippocampus: Potential Role in Impaired Synaptic Plasticity and Cognitive Decline.
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Academic Article
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Nrf2 deficiency in aged mice exacerbates cellular senescence promoting cerebrovascular inflammation.
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Academic Article
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Single-cell RNA sequencing identifies senescent cerebromicrovascular endothelial cells in the aged mouse brain.
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Academic Article
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Obesity-induced cognitive impairment in older adults: a microvascular perspective.
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Academic Article
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Role of age-related alterations of the cerebral venous circulation in the pathogenesis of vascular cognitive impairment.
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Academic Article
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Age-related decline in peripheral vascular health predicts cognitive impairment.
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Academic Article
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Nicotinamide mononucleotide (NMN) treatment attenuates oxidative stress and rescues angiogenic capacity in aged cerebromicrovascular endothelial cells: a potential mechanism for the prevention of vascular cognitive impairment.
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Academic Article
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Fusogenic liposomes effectively deliver resveratrol to the cerebral microcirculation and improve endothelium-dependent neurovascular coupling responses in aged mice.
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Academic Article
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Aging exacerbates obesity-induced cerebromicrovascular rarefaction, neurovascular uncoupling, and cognitive decline in mice.
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Academic Article
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Circulating IGF-1 deficiency exacerbates hypertension-induced microvascular rarefaction in the mouse hippocampus and retrosplenial cortex: implications for cerebromicrovascular and brain aging.
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Academic Article
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Treatment with the mitochondrial-targeted antioxidant peptide SS-31 rescues neurovascular coupling responses and cerebrovascular endothelial function and improves cognition in aged mice.
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Academic Article
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Repeated Valsalva maneuvers promote symptomatic manifestations of cerebral microhemorrhages: implications for the pathogenesis of vascular cognitive impairment in older adults.
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Academic Article
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Whole brain radiation-induced vascular cognitive impairment: mechanisms and implications.
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Academic Article
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Functional vascular contributions to cognitive impairment and dementia: mechanisms and consequences of cerebral autoregulatory dysfunction, endothelial impairment, and neurovascular uncoupling in aging.
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Academic Article
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Cerebromicrovascular dysfunction predicts cognitive decline and gait abnormalities in a mouse model of whole brain irradiation-induced accelerated brain senescence.
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Academic Article
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Nrf2 Deficiency Exacerbates Obesity-Induced Oxidative Stress, Neurovascular Dysfunction, Blood-Brain Barrier Disruption, Neuroinflammation, Amyloidogenic Gene Expression, and Cognitive Decline in Mice, Mimicking the Aging Phenotype.
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Academic Article
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CD82-TRPM7-Numb signaling mediates age-related cognitive impairment.
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Academic Article
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Retinal biomarkers for Alzheimer's disease and vascular cognitive impairment and dementia (VCID): implication for early diagnosis and prognosis.
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Academic Article
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Pharmacologically-induced neurovascular uncoupling is associated with cognitive impairment in mice.
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Academic Article
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Recent Developments in Understanding Brain Aging: Implications for Alzheimer's Disease and Vascular Cognitive Impairment.
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Academic Article
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Impaired neurovascular coupling in aging and Alzheimer's disease: Contribution of astrocyte dysfunction and endothelial impairment to cognitive decline.
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Academic Article
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Hypertension-induced synapse loss and impairment in synaptic plasticity in the mouse hippocampus mimics the aging phenotype: implications for the pathogenesis of vascular cognitive impairment.
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Academic Article
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Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice.
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Academic Article
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Whole brain irradiation in mice causes long-term impairment in astrocytic calcium signaling but preserves astrocyte-astrocyte coupling.
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Grant
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Vasoprotection by Caloric Restriction Mimetics in Aging
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Grant
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Effects of Radiation on Brain Microvasculature and Cognition
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Grant
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Age-related vascular cognitive impairment: role of endothelial senescence
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Grant
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Microvascular mechanisms of neuroinflammation: role of Nrf2
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Grant
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Chemotherapy-induced vascular cognitive impairment: role of endothelial senescence
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Grant
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Cerebromicrovascular rejuvenation by heterochronic blood exchange
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Academic Article
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Hypertension-induced cognitive impairment: from pathophysiology to public health.
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Academic Article
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Microvascular dysfunction and neurovascular uncoupling are exacerbated in peripheral artery disease, increasing the risk of cognitive decline in older adults.
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Academic Article
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Cerebral venous congestion exacerbates cerebral microhemorrhages in mice.
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Academic Article
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Measurements of cerebral microvascular blood flow, oxygenation, and morphology in a mouse model of whole-brain irradiation-induced cognitive impairment by two-photon microscopy and optical coherence tomography: evidence for microvascular injury in the cerebral white matter.
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Academic Article
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Gait variability predicts cognitive impairment in older adults with subclinical cerebral small vessel disease.
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Academic Article
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Accelerated cerebromicrovascular senescence contributes to cognitive decline in a mouse model of paclitaxel (Taxol)-induced chemobrain.
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Academic Article
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Vascular mechanisms leading to progression of mild cognitive impairment to dementia after COVID-19: Protocol and methodology of a prospective longitudinal observational study.
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Academic Article
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The Role of Methionine-Rich Diet in Unhealthy Cerebrovascular and Brain Aging: Mechanisms and Implications for Cognitive Impairment.
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Academic Article
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Impaired Neurovascular Coupling and Increased Functional Connectivity in the Frontal Cortex Predict Age-Related Cognitive Dysfunction.
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